This includes bone and joint infections, intra abdominal infections, certain type of infectious diarrhea, respiratory tract infections, skin infections, typhoid fever, and urinary tract infections, among others. Ciprofloxacin is used to treat a wide variety of infections, including infections of bones and joints, endocarditis, gastroenteritis, malignant otitis externa, respiratory tract infections, cellulitis, urinary tract infections, prostatitis, anthrax, and chancroid. Ciprofloxacin only treats bacterial infections; it does not treat viral infections such as the common cold. For certain uses including acute sinusitis, lower respiratory tract infections and uncomplicated gonorrhea, ciprofloxacin is not considered a first-line agent. Ciprofloxacin occupies an important role in treatment guidelines issued by major medical societies for the treatment of serious infections, especially those likely to be caused by Gram-negative bacteria, including Pseudomonas aeruginosa. For example, ciprofloxacin in combination with metronidazole is one of several first-line antibiotic regimens recommended by the Infectious Diseases Society of America for the treatment of community-acquired abdominal infections in adults. In other cases, treatment guidelines are more restrictive, recommending in most cases that older, narrower-spectrum drugs be used as first-line therapy for less severe infections to minimize fluoroquinolone-resistance development. Ciprofloxacin is active against a broad range of bacteria including both gram-negative & gram-positive bacteria, the most susceptible ones are the aerobic gram-negative bacilli, especially the Enterobacteriaceae and Neisseria. Ciprofloxacin is effective in a broad range of infections. Because of wide-spectrum bactericidal activity, oral efficacy and good tolerability, it is being extensively employed for blind therapy of any infection, but should not be used for minor cases or where gram-positive organisms and /or anaerobes are primarily causative. In severe infections, therapy may be initiated by i.v.
Ciprofloxacin 500 MG Tablet is an antibiotic that is used to treat a variety of bacterial infections such as bronchitis, pneumonia, gonococcal infection, etc. This medicine is not recommended for use in case of a common cold, flu, or other viral infections since it is active against infections caused by bacteria only. This medicine should be used with caution in the elderly population as it increases the risk of tendinitis and tendon rupture. This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects. Take this medicine with or without food, as directed by your doctor. Its empirical formula is C17H18FN3O3 and MW is 331.3. The chemical structure is: Ciprofloxacin inhibits the enzyme bacterial DNA gyrase and prevents replication of bacterial DNA during bacterial growth and reproduction. Ciprofloxacin is well absorbed after oral administration. Blood concentrations of intravenously administered drug are similar to those of orally administered drug. Ciprofloxacin is active against many gram-positive bacteria and gram-negative bacteria. Ciprofloxacin has rapidly bactericidal activity and high potency. Protective intestinal streptococci and anaerobes are spared. Dose modification is needed in patients of renal impairment. Caution in paediatric, geriatric, pregnant and nursing patients.
Start studying ATI Pharm Chapter 46 Urinary Tract Infections. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Ciprofloxacin. Ciprofloxacin Therapeutic uses, Clinical uses, Indications, Dosage, Side Effects, Warnings, Interactions, Precautions, Contraindications & Brand names Ciprofloxacin is the prototype Fluoroquinolones FQ & most potent first generation FQ, used to treat different types of bacterial infections.