Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill. Get Started Comment: I had a large rash outbreak appear on right shoulder upper right chest and neck. t hurt and I assume it was an allergy, day two redness went down but I reached for a Dr.; I was not able so see a Dr until day 3 and I started Valacyclovir 3x a day 7 days th ... I had redness and tingling days before but since its my first time I didnâ?? Show Full Comment Comment: I had a large rash outbreak appear on right shoulder upper right chest and neck. t hurt and I assume it was an allergy, day two redness went down but I reached for a Dr.; I was not able so see a Dr until day 3 and I started Valacyclovir 3x a day 7 days then. I had redness and tingling days before but since its my first time I didnâ?? Pain and stiffness started for me on day 4 and got worst the next 3 days as the rash and blisters dried. No problems with the medication but I probably started too late for it to help. Hide Full Comment Comment: Had bad pain and was nauseous for two weeks before shingles rash showed up. The caplets are huge so I had difficulty taking them, finally cutting them into eighths for ease of taking. Valacyclovir (Valtrex, marketed by Glaxo Smith Kline) and acyclovir (Zovirax, marketed by Sanofi-Aventis) are used mainly for treatment of genital herpes. Both are antiviral drugs and can be taken orally to shorten herpes symptoms or to prevent this infection from recurring in healthy individuals. Acyclovir pills had been in use from 1991 and enjoying the status of a first-of-its-kind antiviral drug for genital herpes treatment, until Valtrex was approved by the US Food and Drug Administration (FDA) 4 years later in 1995. The valacyclovir vs acyclovir debate started since then and it still remains a matter of research interest as to which drug you can use to cope with herpes better. Valacyclovir advantages Valacyclovir has a number of key advantages over other similar antiviral medications. Clinical trials have shown that this drug has greater effectiveness in dealing with the herpes simplex virus (HSV) or the varicella zoster virus (VZV), compared to acyclovir or other drugs. Another plus factor of Valtrex is that it is probably the only medicine that can reduce the risk of herpes transmission, given that safe sex methods are used.
Acyclovir and Valaciclovir are two antiviral drugs. Because these two are in the same class, their mechanism of action is similar. Acyclovir Acyclovir is an antiviral drug synthesized using the nucleoside extracted from the sponge Cryptotethya crypta. It is available in the market under many brand names. Acyclovir is a very commonly used drug, and the commonest indication is Herpes viral infections. It may be used in pregnancy if the benefits outweigh the risks only. The mechanism of action of acyclovir is complicated. Once the drug enters the body the viral enzyme called thymidine kinase converts it to acyclovir monophosphate. Then, cellular kinase enzymes convert it into acyclovir triphosphate. This final product blocks DNA replication and viral reproduction. Acyclovir is very effective against many species of herpes virus family, and resistance to the drug action is encountered very rarely. Therefore, if taken in tablet form the amount that reaches the blood is small. Therefore to obtain high concentrations, acyclovir should be given intravenous. Half-life is the time taken to reduce the concentration by half. Of experiencing at least one recurrence during the treatment period in each group. Background Genital herpes is a sexually transmitted disease (STD) related to herpes simplex virus type 1 (HSV-1) or 2 (HSV-2). Treatment options in patients experiencing recurrences of genital herpes include no treatment, symptomatic treatment, episodic antiviral treatment for a few days each time a recurrence occurs, and suppressive daily continuous treatment. In some people infected with this virus, painful mucocutaneous vesicles develop in a small zone of the genital area and evolve into erosions and crusts. Study characteristics A total of 26 trials including 6950 patients were included in this , we are uncertain as to how much a difference there are likely to make, because of issues with the conduct and reporting of studies, and inconsistency of their results. The quality of the evidence is low and we think that the size of the effects is likely to change with more with acyclovir, valacyclovir or famciclovir in pacients experiencing at least four recurrences of genital herpes per year decreases the number of pacients with at least one recurrence as compared with Genital herpes is caused by herpes simplex virus 1 (HSV-1) or 2 (HSV-2). Some infected people experience outbreaks of genital herpes, typically, characterized by vesicular and erosive localized painful genital lesions. , the search portal of the World Health Organization International Clinical Trials Registry Platform and pharmaceutical company databases up to February 2014. We also searched US Food and Drug Administration databases and proceedings of seven congresses to a maximum of 10 years.
Valacyclovir effectiveness. it is more expensive than acyclovir. The only research study showed a 50% reduction in transmission on valacyclovir Valtrex vs. Nov 14, 2014. Valtrex is the brand name for valacyclovir, an antiviral drug used to treat infections caused by. Let your doctor know if any of these side effects persist or get worse. Since Valtrex is very similar to acyclovir Zovirax, you should not take the two. Delaying treatment can lessen the effectiveness of Valtrex.